The effects of the aqueous crude extract (5%) of Eugenia punicifolia on cholinergic nicotinic neurotransmission were investigated. Actions of. Eugenia punicifolia (Kunth) DC (Myrtaceae), popularly known as pedra-ume-caĆ”, pedra-ume, murta, or muta, is a shrub found mainly in the. Figure 16 Body weight evolution in rats with acetic acid-induced gastric ulcers treated with oral administration of vehicle, lansoprazole.

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Eugenia punicifolia Beach Cherry. Preparation of the plant extract. Wang XJ L- Editor: Intact female rats; C: Berg Eugenia psammophila Diels Eugenia psychotrioides Mart. In this rat study involving males, intact cycling females, and ovariectomized females, gastric ulcers were induced using acetic acid. This effect is modulated by female sex hormones. Wound formation and subsequent healing represent dynamic processes of extracellular matrix remodeling, mainly influenced by Eugeniia and MMP Determination of PGE fugenia levels.

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Syzygium samarangense Wax Jambu. Berg Eugenia pungens var. We performed an in vitro scratch-wound test to determine whether HEEP possesses cell proliferation activity. Statistical analysis The statistical methods of this study were eugeni by Dr.

After extraction, the samples were treated with Laemmili buffer 0. Vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction.


Eugenia punicifolia (Kunth) DC. | Plants of the World Online | Kew Science

Bears 1″, red, shiny fruits that are occasionally tinged with orange. The rationale behind such combinations is frequently questioned, and it remains challenging to assess the individual contribution of each component to the overall activity of the herbal combination preparation. The data represent relative expression of caspase-3 normalized to the expression of housekeeping genes actin.

Differential healing periods of the acetic acid ulcer model in rats and cats. An overview of acetic acid ulcer models–the history and state of the art of peptic ulcer research.

The anti-ulcerogenic activity of estrogen was previously explained by its stimulating effect on parietal cell activity and maintenance of mucus integrity[ 34 ].

Growth factors such as EGF activate epithelial cell migration and proliferation, accelerating wound and ulcer healing in vivo and in vitro [ 5737 ]. Essential oil of Cymbopogon citratus lemongrass and geraniol, but not citral, promote gastric healing activity in mice.

Berg Eugenia polyphylla O. After extraction, the samples were treated with Laemmili buffer 0. Does the gastroprotective action of a medicinal plant ensure healing effects?

The proliferation ability of fibroblasts exposed to HEEP was assessed using the scratch-wound assay, according to a protocol previously described by Balekar et al[ 24 ], with a few modifications.

These results corroborate the findings of Baragi et al[ 53 ], namely that the expression of MMP-2 remained constant throughout the ulcer healing phase. A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction.


Gastric ulcer healing is a complex and genetically-programmed dynamic process[ 37 ]. Nomenclatural notes on Brazilian Myrtaceae Phytotaxa 8: Therefore, alternative therapies for gastric ulcers are desirable[ 9 ].

Eugenia punicifolia (Kunth) DC.

Role of metalloproteinases in the development and healing of acetic acid-induced gastric ulcer in rats. It is well-established that myofibroblasts are an important component of wound healing[ 38 eugdnia, responsible for extracellular matrix production, morphogenesis, and the inflammatory process involved in tissue repair[ 38 – 40 ]. Journal Information of This Article. Berg Myrtus arbutifolia O.

These findings are useful for developing novel and safe therapies for gastric ulcers. Additionally, HEEP enhanced fibroblast proliferation and migration into a wounded area in vitroconfirming its healing effect.

Berg Eugenia romana punicioflia. A new method for the production of chronic gastric ulcer in rats and the effect of several drugs on its healing.

Leave in for 2 months and do the planting from October to December. J Clin Biochem Nutr.